DelveInsight’s “Hidradenitis Suppurativa Market Insights” report includes a comprehensive understanding of current treatment practices, hidradenitis suppurativa emerging drugs, market share of individual therapies, and historical, current as well as forecasted hidradenitis suppurativa market size from 2019 to 2032, segmented into the 7MM [the United States, the EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan].
Key Takeaways from the Hidradenitis Suppurativa Market Report
Discover which therapies are expected to grab major hidradenitis suppurativa market share @ Hidradenitis Suppurativa Market Report
Hidradenitis Suppurativa Overview
Hidradenitis suppurativa is a complex dermatological disease characterized by recurrent painful nodules and suppuration in areas such as the axilla and groin. It is also known as Acne inversa and there is no biological or pathological test to facilitate diagnosis; its clinical features and chronicity can define it.
The exact cause of hidradenitis suppurativa is unclear, but the condition probably results from a combination of genetic and environmental factors. Lumps develop as a result of blocked hair follicles. It is more common in women than men, and in obese and smokers, hidradenitis suppurativa is likely to worsen the symptoms
The symptoms of hidradenitis suppurativa range from mild to severe. It causes a mixture of boil-like lumps, blackheads, cysts, scarring, and channels in the skin that leak pus. Scoring systems for the assessment of hidradenitis suppurativa severity include Hurley staging, Physician’s Global Assessment (PGA), the modified Sartorius score (MSS), and the hidradenitis suppurativa severity index (HSSI).
Systemic therapies, mainly antibiotics and retinoids, are the treatment’s mainstay. Topical therapies are mainly used in cases of mild to moderate disease conditions. Adalimumab (Humira) is the only approved drug for treating moderate to severe hidradenitis suppurativa.
Hidradenitis Suppurativa Epidemiology Segmentation
DelveInsight estimates that there were approximately 1.2 million hidradenitis suppurativa diagnosed prevalent cases in the 7MM in 2021. Among the EU5 countries, Germany had the highest number of hidradenitis suppurativa diagnosed prevalent cases in 2021.
The hidradenitis suppurativa market report proffers epidemiological analysis for the study period 2019–2032 in the 7MM segmented into
Download the report to understand which factors are driving hidradenitis suppurativa epidemiology trends @ Hidradenitis Suppurativa Epidemiological Insights
Hidradenitis Suppurativa Treatment Market
The treatment management usually requires a combination of lifestyle changes, medical therapy, laser or surgical intervention and considerable psychological support. Several pharmacological treatment options include topical and systemic antibiotics, corticosteroids, anti-androgen therapy, systemic retinoids, and immunosuppressive agents, including biologics.
In a small study, Metformin has been used to treat metabolic syndrome associated with hidradenitis suppurativa and has been reported to reduce hidradenitis suppurativa disease activity effectively. Laser hair removal with a 1,064nm laser has shown promise, but many patients cannot afford this treatment due to limited insurance coverage. Humira (Abbvie) is the first and only approved drug for Moderate to Severe hidradenitis suppurativa. In September 2015, the US Food and Drug Administration (FDA) approved Humira to treat moderate to severe hidradenitis suppurativa.
The approval of Humira is a critical milestone in the lives of people with hidradenitis suppurativa who, up until this point, had no approved treatments. The product was approved by the European Commission (EC), in July 2015, for the treatment of active moderate to severe hidradenitis suppurativa in adults with an inadequate response to conventional systemic hidradenitis suppurativa treatment.
Humira was designated for the indication of hidradenitis suppurativa as an orphan drug in 2017 and was approved for the indication of hidradenitis suppurativa for the first time in Japan in February 2019. Humira is actually the only drug in Japan for hidradenitis suppurativa indication.
Even though hidradenitis suppurativa is affecting the lives of millions of people worldwide, there are not many treatment options to treat the underlying cause, nor has there been an improvement in therapeutic options in the last several decades. With only one approved drug in the market, i.e., Humira, there is a high need for alternative therapies due to serious adverse events associated with Adalimumab, including injection site serious infections.
To know more about hidradenitis suppurativa treatment, visit @ Hidradenitis Suppurativa Treatment Guidelines
Hidradenitis Suppurativa Pipeline Therapies and Key Companies
Learn more about the hidradenitis suppurativa therapies in clinical trials @ Drugs for Hidradenitis Suppurativa Treatment
Hidradenitis Suppurativa Market Dynamics
Hidradenitis suppurativa market is currently having vast pipeline therapies targeting interleukins, including (i.e., IL-17, IL-1), anti-TNF, JAKi, and anti-complement factor. The upcoming therapies of hidradenitis suppurativa are expected to come with a patient-convenient Route of administration and are also expected to increase the treatment duration.
In the current treatment market, only HUMIRA is approved for the treatment of moderate to severe hidradenitis suppurativa with modest efficacy and, therefore, provides potentially lucrative market opportunities. No treatment options are available in relapsed/ refractory patients to HUMIRA. However, off-label therapies like antibiotics and retinoids are still the treatment backbone of hidradenitis suppurativa. There are no definite biomarkers available for the early and progressive forms of the disease.
The expected entry of biosimilars of HUMIRA from 2023 in the US will erode the market sales of HUMIRA. Moreover, the market value of HUMIRA in Europe has already started declining from 2018, and sales value decline is expected to be much faster in future years due to multiple launches of biosimilars in 2019 and as well as in upcoming years.
Scope of the Hidradenitis Suppurativa Market Report
Discover more about drugs for hidradenitis suppurativa in development @Hidradenitis Suppurativa Clinical Trials
Table of Contents
1.
Hidradenitis Suppurativa Market Key Insights
2.
Hidradenitis Suppurativa Market Report Introduction
3.
Hidradenitis Suppurativa Market Overview at a Glance
4.
Hidradenitis Suppurativa Market Executive Summary
5.
Hidradenitis Suppurativa Key Events
6.
Epidemiology and Market Methodology
7.
Disease Background and Overview
8.
Hidradenitis Suppurativa Treatment and Management
9.
Hidradenitis Suppurativa Epidemiology and Patient Population
9.1
Key Finding
9.2
Assumptions and Rationale
9.3
Total Prevalent Population of Hidradenitis Suppurativa in the 7MM
9.4
United States
9.5
EU5
9.6
Japan
10.
Patient Journey
11
Key Endpoints in Hidradenitis Suppurativa Clinical Trials
12.
Hidradenitis Suppurativa Marketed Drugs
13.
Hidradenitis Suppurativa Emerging Drugs
14.
Seven Major Hidradenitis Suppurativa Market Analysis
14.1
14.2
Market Outlook
14.3
Attribute Analysis
14.4
Key Market Forecast Assumptions
14.5
Total Market Size of Hidradenitis Suppurativa in the 7MM
14.6
14.7
14.8
15.
Unmet Needs
16.
SWOT Analysis
17.
Market Access and Reimbursement
18.
Appendix
19.
DelveInsight Capabilities
20.
Disclaimer
21.
About DelveInsight
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